Glucose Regulates Rat Beta Cell Number through Age-Dependent Effects on Beta Cell Survival and Proliferation

BACKGROUND: Glucose effects on beta cell survival and DNA-synthesis suggest a role as regulator of beta cell mass but data on beta cell numbers are lacking. We examined outcome of these influences on the number of beta cells isolated at different growth stages in their population. METHODS: Beta cell...

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Detalles Bibliográficos
Autores principales: Assefa, Zerihun, Lavens, Astrid, Steyaert, Christophe, Stangé, Geert, Martens, Geert A., Ling, Zhidong, Hellemans, Karine, Pipeleers, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887027/
https://www.ncbi.nlm.nih.gov/pubmed/24416358
http://dx.doi.org/10.1371/journal.pone.0085174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887027/
https://www.ncbi.nlm.nih.gov/pubmed/24416358
http://dx.doi.org/10.1371/journal.pone.0085174

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