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Transgenic Expression of MicroRNA-181d Augments the Stress-Sensitivity of CD4(+)CD8(+) Thymocytes

Physiological stress resulting from infections, trauma, surgery, alcoholism, malnutrition, and/or pregnancy results in a substantial depletion of immature CD4(+)CD8(+) thymocytes. We previously identified 18 distinct stress-responsive microRNAs (miRs) in the thymus upon systemic stress induced by li...

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Detalles Bibliográficos
Autores principales: Belkaya, Serkan, van Oers, Nicolai S. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887031/
https://www.ncbi.nlm.nih.gov/pubmed/24416377
http://dx.doi.org/10.1371/journal.pone.0085274