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Membrane-anchored chemokine fusion proteins: A novel class of adjuvants for immunotherapy

Adoptive or active cancer immunotherapy can fail owing to the inefficient recruitment of effector leukocytes to malignant lesions. The intratumoral injection of recombinant proteins comprising a chemokine-derived domain linked to the mucin stalk of chemokine (C-X3-C motif) ligand 1 (CX3CL1) and a gl...

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Detalles Bibliográficos
Autores principales: Nelson, Peter J, Muenchmeier, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887060/
https://www.ncbi.nlm.nih.gov/pubmed/24427544
http://dx.doi.org/10.4161/onci.26619