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Insulin-Like Growth Factor-1 and Bone Morphogenetic Protein-2 Jointly Mediate Prostaglandin E2-Induced Adipogenic Differentiation of Rat Tendon Stem Cells

Tendinopathy is characterized histopathologically by lipid accumulation and tissue calcification. Adipogenic and osteogenic differentiation of tendon stem cells (TSCs) are believed to play key roles in these processes. The major inflammatory mediator prostaglandin E2 (PGE2) has been shown to induce...

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Detalles Bibliográficos
Autores principales: Liu, Junpeng, Chen, Lei, zhou, You, Liu, Xiangzhou, Tang, Kanglai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887066/
https://www.ncbi.nlm.nih.gov/pubmed/24416413
http://dx.doi.org/10.1371/journal.pone.0085469