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IFNγ/IL-10 Co-producing Cells Dominate the CD4 Response to Malaria in Highly Exposed Children

Although evidence suggests that T cells are critical for immunity to malaria, reliable T cell correlates of exposure to and protection from malaria among children living in endemic areas are lacking. We used multiparameter flow cytometry to perform a detailed functional characterization of malaria-s...

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Detalles Bibliográficos
Autores principales: Jagannathan, Prasanna, Eccles-James, Ijeoma, Bowen, Katherine, Nankya, Felistas, Auma, Ann, Wamala, Samuel, Ebusu, Charles, Muhindo, Mary K., Arinaitwe, Emmanuel, Briggs, Jessica, Greenhouse, Bryan, Tappero, Jordan W., Kamya, Moses R., Dorsey, Grant, Feeney, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887092/
https://www.ncbi.nlm.nih.gov/pubmed/24415936
http://dx.doi.org/10.1371/journal.ppat.1003864