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Cell Tropism Predicts Long-term Nucleotide Substitution Rates of Mammalian RNA Viruses
The high rates of RNA virus evolution are generally attributed to replication with error-prone RNA-dependent RNA polymerases. However, these long-term nucleotide substitution rates span three orders of magnitude and do not correlate well with mutation rates or selection pressures. This substitution...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887100/ https://www.ncbi.nlm.nih.gov/pubmed/24415935 http://dx.doi.org/10.1371/journal.ppat.1003838 |