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Acute Versus Chronic Loss of Mammalian Azi1/Cep131 Results in Distinct Ciliary Phenotypes

Defects in cilium and centrosome function result in a spectrum of clinically-related disorders, known as ciliopathies. However, the complex molecular composition of these structures confounds functional dissection of what any individual gene product is doing under normal and disease conditions. As p...

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Detalles Bibliográficos
Autores principales: Hall, Emma A., Keighren, Margaret, Ford, Matthew J., Davey, Tracey, Jarman, Andrew P., Smith, Lee B., Jackson, Ian J., Mill, Pleasantine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887133/
https://www.ncbi.nlm.nih.gov/pubmed/24415959
http://dx.doi.org/10.1371/journal.pgen.1003928