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Structure and Self-Assembly of the Calcium Binding Matrix Protein of Human Metapneumovirus

The matrix protein (M) of paramyxoviruses plays a key role in determining virion morphology by directing viral assembly and budding. Here, we report the crystal structure of the human metapneumovirus M at 2.8 Å resolution in its native dimeric state. The structure reveals the presence of a high-affi...

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Detalles Bibliográficos
Autores principales: Leyrat, Cedric, Renner, Max, Harlos, Karl, Huiskonen, Juha T., Grimes, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887258/
https://www.ncbi.nlm.nih.gov/pubmed/24316400
http://dx.doi.org/10.1016/j.str.2013.10.013