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Mass spectrometry and molecular modeling studies on the inclusion complexes between alendronate and β-cyclodextrin
Complexation of alendronate sodium (AlnNa) with β-cyclodextrin (β-CD) was studied by means of ESI-mass spectrometry. The experimental results show that stable 1:1 inclusion complexes between selected bisphosphonates and β-CD were formed. In addition, complexes with different stoichiometry were obser...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887263/ https://www.ncbi.nlm.nih.gov/pubmed/24431983 http://dx.doi.org/10.1007/s10847-013-0315-0 |