Gemcitabine enhances the efficacy of reovirus-based oncotherapy through anti-tumour immunological mechanisms

BACKGROUND: Reovirus preferentially infects and kills cancer cells and is currently undergoing clinical trials internationally. While oncolysis is the primary mode of tumour elimination, increasing evidence illustrates that reovirus additionally stimulates anti-tumour immunity with a capacity to tar...

Descripción completa

Detalles Bibliográficos
Autores principales: Gujar, S A, Clements, D, Dielschneider, R, Helson, E, Marcato, P, Lee, P W K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887295/
https://www.ncbi.nlm.nih.gov/pubmed/24281006
http://dx.doi.org/10.1038/bjc.2013.695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887295/
https://www.ncbi.nlm.nih.gov/pubmed/24281006
http://dx.doi.org/10.1038/bjc.2013.695

Ejemplares similares