Expression of nuclear survivin in normal skin and squamous cell carcinoma: a possible role in tumour invasion

BACKGROUND: Survivin is detected in few adult normal cells and it is highly expressed in cancer. Nuclear survivin facilitates cell cycle entry, whereas the mitochondrial pool protects cells from apoptosis. Survivin is overexpressed in keratinocyte stem cells (KSCs) and protects them from apoptosis....

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Detalles Bibliográficos
Autores principales: Dallaglio, K, Petrachi, T, Marconi, A, Truzzi, F, Lotti, R, Saltari, A, Morandi, P, Puviani, M, Maiorana, A, Pincelli, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887296/
https://www.ncbi.nlm.nih.gov/pubmed/24196791
http://dx.doi.org/10.1038/bjc.2013.697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887296/
https://www.ncbi.nlm.nih.gov/pubmed/24196791
http://dx.doi.org/10.1038/bjc.2013.697

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