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Design and Analysis of Bar-seq Experiments

High-throughput quantitative DNA sequencing enables the parallel phenotyping of pools of thousands of mutants. However, the appropriate analytical methods and experimental design that maximize the efficiency of these methods while maintaining statistical power are currently unknown. Here, we have us...

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Detalles Bibliográficos
Autores principales: Robinson, David G., Chen, Wei, Storey, John D., Gresham, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887526/
https://www.ncbi.nlm.nih.gov/pubmed/24192834
http://dx.doi.org/10.1534/g3.113.008565