Cargando…

Evaluating the potential of cubosomal nanoparticles for oral delivery of amphotericin B in treating fungal infection

The oral administration of amphotericin B (AmB) has a major drawback of poor bioavailability. The aim of this study was to investigate the potential of glyceryl monoolein (GMO) cubosomes as lipid nanocarriers to improve the oral efficacy of AmB. Antifungal efficacy was determined in vivo in rats aft...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Zhiwen, Chen, Meiwan, Yang, Muhua, Chen, Jian, Fang, Weijun, Xu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888350/
https://www.ncbi.nlm.nih.gov/pubmed/24421641
http://dx.doi.org/10.2147/IJN.S54967