Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin

In spite of the power of phage display technology to identify variant proteins with novel properties in large libraries, it has only been previously applied to one member of the serpin superfamily. Here we describe phage display of human alpha-1 proteinase inhibitor (API) in a T7 bacteriophage syste...

Descripción completa

Detalles Bibliográficos
Autores principales: Scott, Benjamin M., Matochko, Wadim L., Gierczak, Richard F., Bhakta, Varsha, Derda, Ratmir, Sheffield, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888415/
https://www.ncbi.nlm.nih.gov/pubmed/24427287
http://dx.doi.org/10.1371/journal.pone.0084491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888415/
https://www.ncbi.nlm.nih.gov/pubmed/24427287
http://dx.doi.org/10.1371/journal.pone.0084491

Ejemplares similares