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Production of CXC and CC Chemokines by Human Antigen-Presenting Cells in Response to Lassa Virus or Closely Related Immunogenic Viruses, and in Cynomolgus Monkeys with Lassa Fever

The pathogenesis of Lassa fever (LF), a hemorrhagic fever endemic to West Africa, remains unclear. We previously compared Lassa virus (LASV) with its genetically close, but nonpathogenic homolog Mopeia virus (MOPV) and demonstrated that the strong activation of antigen-presenting cells (APC), includ...

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Detalles Bibliográficos
Autores principales: Pannetier, Delphine, Reynard, Stéphanie, Russier, Marion, Carnec, Xavier, Baize, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888467/
https://www.ncbi.nlm.nih.gov/pubmed/24421914
http://dx.doi.org/10.1371/journal.pntd.0002637