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LmaPA2G4, a Homolog of Human Ebp1, Is an Essential Gene and Inhibits Cell Proliferation in L. major

We have identified LmaPA2G4, a homolog of the human proliferation-associated 2G4 protein (also termed Ebp1), in a phosphoproteomic screening. Multiple sequence alignment and cluster analysis revealed that LmaPA2G4 is a non-peptidase member of the M24 family of metallopeptidases. This pseudoenzyme is...

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Detalles Bibliográficos
Autores principales: Norris-Mullins, Brianna, VanderKolk, Kaitlin, Vacchina, Paola, Joyce, Michelle V., Morales, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888471/
https://www.ncbi.nlm.nih.gov/pubmed/24421916
http://dx.doi.org/10.1371/journal.pntd.0002646