The Circadian Clock in Murine Chondrocytes Regulates Genes Controlling Key Aspects of Cartilage Homeostasis

ObjectiveTo characterize the circadian clock in murine cartilage tissue and identify tissue-specific clock target genes, and to investigate whether the circadian clock changes during aging or during cartilage degeneration using an experimental mouse model of osteoarthritis (OA). MethodsCartilage exp...

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Detalles Bibliográficos
Autores principales: Gossan, Nicole, Zeef, Leo, Hensman, James, Hughes, Alun, Bateman, John F, Rowley, Lynn, Little, Christopher B, Piggins, Hugh D, Rattray, Magnus, Boot-Handford, Raymond P, Meng, Qing-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals 2013
Materias:
Chondrocyte Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888512/
https://www.ncbi.nlm.nih.gov/pubmed/23896777
http://dx.doi.org/10.1002/art.38035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888512/
https://www.ncbi.nlm.nih.gov/pubmed/23896777
http://dx.doi.org/10.1002/art.38035

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