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Long-Term Exposure to Concentrated Ambient PM(2.5) Increases Mouse Blood Pressure through Abnormal Activation of the Sympathetic Nervous System: A Role for Hypothalamic Inflammation

Background: Exposure to particulate matter ≤ 2.5 μm in diameter (PM(2.5)) increases blood pressure (BP) in humans and animal models. Abnormal activation of the sympathetic nervous system may have a role in the acute BP response to PM(2.5) exposure. The mechanisms responsible for sympathetic nervous...

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Detalles Bibliográficos
Autores principales: Ying, Zhekang, Xu, Xiaohua, Bai, Yuntao, Zhong, Jixin, Chen, Minjie, Liang, Yijia, Zhao, Jinzhuo, Liu, Dongyao, Morishita, Masako, Sun, Qinghua, Spino, Catherine, Brook, Robert D., Harkema, Jack R., Rajagopalan, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888575/
https://www.ncbi.nlm.nih.gov/pubmed/24240275
http://dx.doi.org/10.1289/ehp.1307151