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Genes involved in innate immunity associated with asbestos-related fibrotic changes

OBJECTIVES: To determine whether genetic polymorphisms in several candidate genes related to innate immunity and protease–antiprotease balance modify individual susceptibility to develop asbestos-related fibrotic pleuropulmonary changes. METHODS: Sixteen polymorphisms from nine genes (NLRP3, CARD8,...

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Detalles Bibliográficos
Autores principales: Kukkonen, Mari K, Vehmas, Tapio, Piirilä, Päivi, Hirvonen, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888604/
https://www.ncbi.nlm.nih.gov/pubmed/24142982
http://dx.doi.org/10.1136/oemed-2013-101555