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Mathematical Model of Dynamic Protein Interactions Regulating p53 Protein Stability for Tumor Suppression
In the field of cancer biology, numerous genes or proteins form extremely complex regulatory network, which determines cancer cell fate and cancer cell survival. p53 is a major tumor suppressor that is lost in more than 50% of human cancers. It has been well known that a variety of proteins regulate...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888710/ https://www.ncbi.nlm.nih.gov/pubmed/24454532 http://dx.doi.org/10.1155/2013/358980 |