Novel SCRG1/BST1 axis regulates self-renewal, migration, and osteogenic differentiation potential in mesenchymal stem cells

Human mesenchymal stem cells (hMSCs) remodel or regenerate various tissues through several mechanisms. Here, we identified the hMSC-secreted protein SCRG1 and its receptor BST1 as a positive regulator of self-renewal, migration, and osteogenic differentiation. SCRG1 and BST1 gene expression decrease...

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Detalles Bibliográficos
Autores principales: Aomatsu, Emiko, Takahashi, Noriko, Sawada, Shunsuke, Okubo, Naoto, Hasegawa, Tomokazu, Taira, Masayuki, Miura, Hiroyuki, Ishisaki, Akira, Chosa, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888969/
https://www.ncbi.nlm.nih.gov/pubmed/24413464
http://dx.doi.org/10.1038/srep03652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888969/
https://www.ncbi.nlm.nih.gov/pubmed/24413464
http://dx.doi.org/10.1038/srep03652

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