Active DNA demethylation is required for complete imprint erasure in primordial germ cells

In mammalian primordial germ cells (PGCs), DNA demethylation is indispensible for parental imprint erasure, which is a reprogramming process essential for normal developmental potential. Thus, it is important to elucidate how DNA demethylation occurs in each imprinted region in PGCs and to determine...

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Detalles Bibliográficos
Autores principales: Kawasaki, Yuki, Lee, Jiyoung, Matsuzawa, Ayumi, Kohda, Takashi, Kaneko-Ishino, Tomoko, Ishino, Fumitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888974/
https://www.ncbi.nlm.nih.gov/pubmed/24413819
http://dx.doi.org/10.1038/srep03658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888974/
https://www.ncbi.nlm.nih.gov/pubmed/24413819
http://dx.doi.org/10.1038/srep03658

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