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Development of a Positive-readout Mouse Model of siRNA Pharmacodynamics
Development of RNAi-based therapeutics has the potential to revolutionize treatment options for a range of human diseases. However, as with gene therapy, a major barrier to progress is the lack of methods to achieve and measure efficient delivery for systemic administration. We have developed a posi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889190/ https://www.ncbi.nlm.nih.gov/pubmed/24253258 http://dx.doi.org/10.1038/mtna.2013.63 |