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Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats

RATIONALE: Some novel antipsychotics manifest antagonistic activity at serotonin-6 receptors; however, little is known about the role of 5-HT6 receptors in ameliorating sensory gating deficits. OBJECTIVE: We evaluated the effects of the combined administration of the 5-HT6 receptor antagonist SB 271...

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Detalles Bibliográficos
Autores principales: Fijał, Katarzyna, Popik, Piotr, Nikiforuk, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889519/
https://www.ncbi.nlm.nih.gov/pubmed/23954911
http://dx.doi.org/10.1007/s00213-013-3234-2