Concentration-Dependent Opposite Effects of 1-Benzyl-1,2,3,4-tetrahydroisoquinoline on Markers of Apoptosis: In Vitro and Ex Vivo Studies

1-Benzyl-1,2,3,4-tetrahydroisoquinoline (1BnTIQ) was shown to be neurotoxic to the dopaminergic neurons, and thus it was proposed to be an endogenous risk factor leading to Parkinson’s disease. In order to better understand the molecular mechanisms of 1BnTIQ—produced toxicity, we examined the impact...

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Detalles Bibliográficos
Autores principales: Wąsik, Agnieszka, Kajta, Małgorzata, Lenda, Tomasz, Antkiewicz-Michaluk, Lucyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889680/
https://www.ncbi.nlm.nih.gov/pubmed/24190811
http://dx.doi.org/10.1007/s12640-013-9436-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889680/
https://www.ncbi.nlm.nih.gov/pubmed/24190811
http://dx.doi.org/10.1007/s12640-013-9436-x

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