Inhibition of LINE-1 retrotransposon-encoded reverse transcriptase modulates the expression of cell differentiation genes in breast cancer cells

Long Interspersed Elements (L1 elements) are biologically active retrotransposons that are capable of autonomous replication using their own reverse transcriptase (RT) enzyme. Expression of the normally repressed RT has been implicated in cancer cell growth. However, at present, little is known abou...

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Detalles Bibliográficos
Autores principales: Patnala, Radhika, Lee, Sung-Hun, Dahlstrom, Jane E., Ohms, Stephen, Chen, Long, Dheen, S. Thameem, Rangasamy, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889873/
https://www.ncbi.nlm.nih.gov/pubmed/24337508
http://dx.doi.org/10.1007/s10549-013-2812-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889873/
https://www.ncbi.nlm.nih.gov/pubmed/24337508
http://dx.doi.org/10.1007/s10549-013-2812-7

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