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Plasma concentrations of soluble IL-2 receptor α (CD25) are increased in type 1 diabetes and associated with reduced C-peptide levels in young patients

AIMS/HYPOTHESIS: Type 1 diabetes is a common autoimmune disease that has genetic and environmental determinants. Variations within the IL2 and IL2RA (also known as CD25) gene regions are associated with disease risk, and variation in expression or function of these proteins is likely to be causal. W...

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Detalles Bibliográficos
Autores principales: Downes, Kate, Marcovecchio, M. Loredana, Clarke, Pamela, Cooper, Jason D., Ferreira, Ricardo C., Howson, Joanna M. M., Jolley, Jennifer, Nutland, Sarah, Stevens, Helen E., Walker, Neil M., Wallace, Chris, Dunger, David B., Todd, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890035/
https://www.ncbi.nlm.nih.gov/pubmed/24264051
http://dx.doi.org/10.1007/s00125-013-3113-8