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Metabolite profiling reveals new insights into the regulation of serum urate in humans

Serum urate, the final breakdown product of purine metabolism, is causally involved in the pathogenesis of gout, and implicated in cardiovascular disease and type 2 diabetes. Serum urate levels highly differ between men and women; however the underlying biological processes in its regulation are sti...

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Detalles Bibliográficos
Autores principales: Albrecht, Eva, Waldenberger, Melanie, Krumsiek, Jan, Evans, Anne M., Jeratsch, Ulli, Breier, Michaela, Adamski, Jerzy, Koenig, Wolfgang, Zeilinger, Sonja, Fuchs, Christiane, Klopp, Norman, Theis, Fabian J., Wichmann, H.-Erich, Suhre, Karsten, Illig, Thomas, Strauch, Konstantin, Peters, Annette, Gieger, Christian, Kastenmüller, Gabi, Doering, Angela, Meisinger, Christa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890072/
https://www.ncbi.nlm.nih.gov/pubmed/24482632
http://dx.doi.org/10.1007/s11306-013-0565-2