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Evaluating Potential Therapies in a Mouse Model of Focal Retinal Degeneration with Age-related Macular Degeneration (AMD)-Like Lesions

Although the mouse has no macula leutea, its neuroretina and retinal pigment epithelium (RPE) can develop lesions mimicking certain features of age-related macular degeneration (AMD). Differences between the Ccl2 and Cx3cr1 double deficient mouse on Crb1(rd8)(rd8) background (DKO(rd8)) and the Crb1(...

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Detalles Bibliográficos
Autores principales: Popp, Nicholas, Chu, Xi K., Shen, Defen, Tuo, Jingsheng, Chan, Chi-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890246/
https://www.ncbi.nlm.nih.gov/pubmed/24432192
http://dx.doi.org/10.4172/2155-9570.1000296