Specific Disruption of Hippocampal Mossy Fiber Synapses in a Mouse Model of Familial Alzheimer's Disease

The earliest stages of Alzheimer's disease (AD) are characterized by deficits in memory and cognition indicating hippocampal pathology. While it is now recognized that synapse dysfunction precedes the hallmark pathological findings of AD, it is unclear if specific hippocampal synapses are parti...

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Detalles Bibliográficos
Autores principales: Wilke, Scott A., Raam, Tara, Antonios, Joseph K., Bushong, Eric A., Koo, Edward H., Ellisman, Mark H., Ghosh, Anirvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890281/
https://www.ncbi.nlm.nih.gov/pubmed/24454724
http://dx.doi.org/10.1371/journal.pone.0084349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890281/
https://www.ncbi.nlm.nih.gov/pubmed/24454724
http://dx.doi.org/10.1371/journal.pone.0084349

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