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Specific Disruption of Hippocampal Mossy Fiber Synapses in a Mouse Model of Familial Alzheimer's Disease
The earliest stages of Alzheimer's disease (AD) are characterized by deficits in memory and cognition indicating hippocampal pathology. While it is now recognized that synapse dysfunction precedes the hallmark pathological findings of AD, it is unclear if specific hippocampal synapses are parti...
Autores principales: | Wilke, Scott A., Raam, Tara, Antonios, Joseph K., Bushong, Eric A., Koo, Edward H., Ellisman, Mark H., Ghosh, Anirvan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890281/ https://www.ncbi.nlm.nih.gov/pubmed/24454724 http://dx.doi.org/10.1371/journal.pone.0084349 |
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