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Arsenic Sulfide Promotes Apoptosis in Retinoid Acid Resistant Human Acute Promyelocytic Leukemic NB4-R1 Cells through Downregulation of SET Protein

Tetra-arsenic tetra-sulfide (As(4)S(4)) is an arsenic compound with anti-tumor activity, especially in acute promyelocytic leukemia (APL) that are resistant to retinoic acid (RA). Although recent studies revealed that the therapeutic action of As(4)S(4) is closely associated with the induction of ce...

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Detalles Bibliográficos
Autores principales: Tian, Yuwang, Liu, Yanfeng, He, Pengcheng, Liu, Feng, Zhou, Naicen, Cheng, Xiaoyan, Shi, Lili, Zhu, Huachao, Zhao, Jing, Wang, Yuan, Zhang, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890287/
https://www.ncbi.nlm.nih.gov/pubmed/24454695
http://dx.doi.org/10.1371/journal.pone.0083184