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The Predictive but Not Prognostic Value of MGMT Promoter Methylation Status in Elderly Glioblastoma Patients: A Meta-Analysis

BACKGROUND: The clinical implication of O6-methylguanine-DNA methyltransferase (MGMT) promoter status is ill-defined in elderly glioblastoma patients. Here we report a meta-analysis to seek valid evidence for its clinical relevance in this subpopulation. METHODS: Literature were searched and reviewe...

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Detalles Bibliográficos
Autores principales: Yin, An-an, Zhang, Lu-hua, Cheng, Jin-xiang, Dong, Yu, Liu, Bo-lin, Han, Ning, Zhang, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890309/
https://www.ncbi.nlm.nih.gov/pubmed/24454798
http://dx.doi.org/10.1371/journal.pone.0085102