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Role of Endoplasmic Reticulum Stress in Rheumatoid Arthritis Pathogenesis
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by abnormal proliferation of synoviocytes, leukocyte infiltration, and angiogenesis. The endoplasmic reticulum (ER) is the site of biosynthesis for all secreted and membrane proteins. The accumulation of unfolded proteins in t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Medical Sciences
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890471/ https://www.ncbi.nlm.nih.gov/pubmed/24431899 http://dx.doi.org/10.3346/jkms.2014.29.1.2 |