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Establishment of a CpG island microarray for analyses of genome-wide DNA methylation in Chinese hamster ovary cells
Optimizing productivity and growth rates of recombinant Chinese hamster ovary (CHO) cells requires insight into the regulation of cellular processes. In this regard, the elucidation of the epigenetic process of DNA methylation, known to influence transcription by a differential occurrence in CpG isl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890572/ https://www.ncbi.nlm.nih.gov/pubmed/24146078 http://dx.doi.org/10.1007/s00253-013-5282-2 |