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Establishment of a CpG island microarray for analyses of genome-wide DNA methylation in Chinese hamster ovary cells

Optimizing productivity and growth rates of recombinant Chinese hamster ovary (CHO) cells requires insight into the regulation of cellular processes. In this regard, the elucidation of the epigenetic process of DNA methylation, known to influence transcription by a differential occurrence in CpG isl...

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Detalles Bibliográficos
Autores principales: Wippermann, Anna, Klausing, Sandra, Rupp, Oliver, Albaum, Stefan P., Büntemeyer, Heino, Noll, Thomas, Hoffrogge, Raimund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890572/
https://www.ncbi.nlm.nih.gov/pubmed/24146078
http://dx.doi.org/10.1007/s00253-013-5282-2