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The drug:H(+) antiporters of family 2 (DHA2), siderophore transporters (ARN) and glutathione:H(+) antiporters (GEX) have a common evolutionary origin in hemiascomycete yeasts

BACKGROUND: The Saccharomyces cerevisiae 14-spanner Drug:H(+) Antiporter family 2 (DHA2) are transporters of the Major Facilitator Superfamily (MFS) involved in multidrug resistance (MDR). Although poorly characterized, DHA2 family members were found to participate in the export of structurally and...

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Detalles Bibliográficos
Autores principales: Dias, Paulo Jorge, Sá-Correia, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890622/
https://www.ncbi.nlm.nih.gov/pubmed/24345006
http://dx.doi.org/10.1186/1471-2164-14-901