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Loss of molars early in life develops behavioral lateralization and impairs hippocampus-dependent recognition memory

BACKGROUND: Using senescence-accelerated mouse prone 8 (SAMP8), we examined whether reduced mastication from a young age affects hippocampal-dependent cognitive function. We anesthetized male SAMP8 mice at 8 weeks of age and extracted all maxillary molar teeth of half the animals. The other animals...

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Detalles Bibliográficos
Autores principales: Kawahata, Masatsuna, Ono, Yumie, Ohno, Akinori, Kawamoto, Shoichi, Kimoto, Katsuhiko, Onozuka, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890624/
https://www.ncbi.nlm.nih.gov/pubmed/24387332
http://dx.doi.org/10.1186/1471-2202-15-4