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Critical assessment of coalescent simulators in modeling recombination hotspots in genomic sequences

BACKGROUND: Coalescent simulation is pivotal for understanding population evolutionary models and demographic histories, as well as for developing novel analytical methods for genetic association studies for DNA sequence data. A plethora of coalescent simulators are developed, but selecting the most...

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Detalles Bibliográficos
Autores principales: Yang, Tao, Deng, Hong-Wen, Niu, Tianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890628/
https://www.ncbi.nlm.nih.gov/pubmed/24387001
http://dx.doi.org/10.1186/1471-2105-15-3