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Critical assessment of coalescent simulators in modeling recombination hotspots in genomic sequences
BACKGROUND: Coalescent simulation is pivotal for understanding population evolutionary models and demographic histories, as well as for developing novel analytical methods for genetic association studies for DNA sequence data. A plethora of coalescent simulators are developed, but selecting the most...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890628/ https://www.ncbi.nlm.nih.gov/pubmed/24387001 http://dx.doi.org/10.1186/1471-2105-15-3 |