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Discovery of MLL1 binding units, their localization to CpG Islands, and their potential function in mitotic chromatin
BACKGROUND: Mixed Lineage Leukemia 1 (MLL1) is a mammalian ortholog of the Drosophila Trithorax. In Drosophila, Trithorax complexes transmit the memory of active genes to daughter cells through interactions with Trithorax Response Elements (TREs). However, despite their functional importance, nothin...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890651/ https://www.ncbi.nlm.nih.gov/pubmed/24373511 http://dx.doi.org/10.1186/1471-2164-14-927 |