Discovery of MLL1 binding units, their localization to CpG Islands, and their potential function in mitotic chromatin

BACKGROUND: Mixed Lineage Leukemia 1 (MLL1) is a mammalian ortholog of the Drosophila Trithorax. In Drosophila, Trithorax complexes transmit the memory of active genes to daughter cells through interactions with Trithorax Response Elements (TREs). However, despite their functional importance, nothin...

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Detalles Bibliográficos
Autores principales: Bina, Minou, Wyss, Phillip, Novorolsky, Elise, Zulkelfi, Noorfatin, Xue, Jing, Price, Randi, Fay, Matthew, Gutmann, Zach, Fogler, Brian, Wang, Daidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890651/
https://www.ncbi.nlm.nih.gov/pubmed/24373511
http://dx.doi.org/10.1186/1471-2164-14-927

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