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Post-Synthetic Regulation of HS Structure: The Yin and Yang of the Sulfs in Cancer

Heparan sulfate (HS) is a complex polysaccharide that takes part in most major cellular processes, through its ability to bind and modulate a very large array of proteins. These interactions involve saccharide domains of specific sulfation pattern (S-domains), the assembly of which is tightly orches...

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Detalles Bibliográficos
Autores principales: Vivès, Romain R., Seffouh, Amal, Lortat-Jacob, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890690/
https://www.ncbi.nlm.nih.gov/pubmed/24459635
http://dx.doi.org/10.3389/fonc.2013.00331