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Clinical utility of the oral JAK inhibitor tofacitinib in the treatment of rheumatoid arthritis

Immune/inflammatory cells act in rheumatoid arthritis (RA)-affected patients by synthesizing several inflammatory mediators, including cytokines that initiate intracellular signaling. Recently, small molecule inhibitors of transduction and transcription signals that influence the intracellular pathw...

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Detalles Bibliográficos
Autores principales: Cutolo, Maurizio, Meroni, Marianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890964/
https://www.ncbi.nlm.nih.gov/pubmed/24453498
http://dx.doi.org/10.2147/JIR.S35901