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Alu- and 7SL RNA Analogues Suppress MCF-7 Cell Viability through Modulating the Transcription of Endoplasmic Reticulum Stress Response Genes

11% of the human genome is composed of Alu-retrotransposons, whose transcription by RNA polymerase III (Pol III) leads to the accumulation of several hundreds to thousands of Alu-RNA copies in the cytoplasm. Expression of Alu-RNA Pol III is significantly increased at various levels of stress, and th...

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Detalles Bibliográficos
Autores principales: Baryakin, D.N., Semenov, D.V., Savelyeva, A.V., Koval, O.A., Rabinov, I.V., Kuligina, E.V., Richter, V.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890993/
https://www.ncbi.nlm.nih.gov/pubmed/24455187