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Ambivalent roles of carboxypeptidase B in the lytic susceptibility of fibrin()

BACKGROUND: Removal of C-terminal lysine residues that are continuously exposed in lysing fibrin is an established anti-fibrinolytic mechanism dependent on the plasma carboxypeptidase TAFIa, which also removes arginines that are exposed at the time of fibrinogen clotting by thrombin. OBJECTIVE: To e...

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Detalles Bibliográficos
Autores principales: Kovács, András, Szabó, László, Longstaff, Colin, Tenekedjiev, Kiril, Machovich, Raymund, Kolev, Krasimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891004/
https://www.ncbi.nlm.nih.gov/pubmed/24094605
http://dx.doi.org/10.1016/j.thromres.2013.09.017