Unpredicted Severe Toxicity after 5-Fluorouracil Treatment due to Dihydropyrimidine Dehydrogenase Deficiency

Dihydropyrimidine dehydrogenase (DPD) is the initial and rate-limiting enzyme in the catabolism of 5-fluorouracil (5-FU). Thus, patients with a DPD deficiency are at risk of developing severe 5-FU-associated toxicity. A 37-year-old female with gastric cancer underwent a curative operation, followed...

Descripción completa

Detalles Bibliográficos
Autores principales: Baek, Jin Ho, Kim, Jong Gwang, Kim, Shi Nae, Kim, Dong Hwan, Sohn, Sang Kyun, Hong, Young Jun, Lee, Kyu Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2006
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891063/
https://www.ncbi.nlm.nih.gov/pubmed/16646564
http://dx.doi.org/10.3904/kjim.2006.21.1.43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891063/
https://www.ncbi.nlm.nih.gov/pubmed/16646564
http://dx.doi.org/10.3904/kjim.2006.21.1.43

Ejemplares similares