Neutrophil Elastase Causes MUC5AC Mucin Synthesis Via EGF Receptor, ERK and NF-kB Pathways in A549 Cells

BACKGROUND: Neutrophil elastase (NE) was found to increase the respiratory mucin gene, MUC5AC, although the molecular mechanisms of this process remain unknown. We attempted to determine the signal transduction pathway through which NE induces MUC5AC gene expression in bronchial epithelial cells. ME...

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Detalles Bibliográficos
Autores principales: Song, Jeong-Sup, Cho, Kyung-Sook, Yoon, Hyung-Kyu, Moon, Hwa-Sik, Park, Sung-Hak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2005
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891072/
https://www.ncbi.nlm.nih.gov/pubmed/16491824
http://dx.doi.org/10.3904/kjim.2005.20.4.275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891072/
https://www.ncbi.nlm.nih.gov/pubmed/16491824
http://dx.doi.org/10.3904/kjim.2005.20.4.275

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