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Structure-Activity Relationships of 3,3′-Phenylmethylene-bis-4-hydroxycoumarins: Selective and Potent Inhibitors of Gram-Positive Bacteria

Dicoumarols and coumarin derivatives have shown a variety of pharmaceutical activities and have been found to be potent inhibitor for the NAD(P)H-dependent flavoproteins. In this report, dicoumarol and its derivatives containing the substituted benzene ring at the methylenebis position were synthesi...

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Detalles Bibliográficos
Autores principales: Petnapapun, Kanokporn, Chavasiri, Warinthorn, Sompornpisut, Pornthep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891237/
https://www.ncbi.nlm.nih.gov/pubmed/24459419
http://dx.doi.org/10.1155/2013/178649