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Anti-Tumor Effect of Rutin on Human Neuroblastoma Cell Lines through Inducing G2/M Cell Cycle Arrest and Promoting Apoptosis

Aims. To further investigate the antineuroblastoma effect of rutin which is a type of flavonoid. Methods. The antiproliferation of rutin in human neuroblastoma cells LAN-5 were detected by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Chemotaxis of LAN-5 cells was assesse...

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Detalles Bibliográficos
Autores principales: Chen, Hongyan, Miao, Qing, Geng, Miao, Liu, Jing, Hu, Yazhuo, Tian, Lei, Pan, Jingkun, Yang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891239/
https://www.ncbi.nlm.nih.gov/pubmed/24459422
http://dx.doi.org/10.1155/2013/269165