Effect of IgA Aggregates on Transforming Growth Factor-β1 Production in Human Mesangial Cells and the Intraglomerular Expression of Transforming Growth Factor-β1 in Patients with IgA Nephropathy

BACKGROUND: Transforming growth factor-β (TGF-β) stimulates renal fibrosis in various renal diseases including IgA nephropathy. METHODS: We examined whether immunoglobulin A (IgA) stimulated TGF-β1 synthesis in human mesangial cells (MCs), and whether this effect was mediated through the protein kin...

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Detalles Bibliográficos
Autores principales: Han, Sang-Youb, Ihm, Chun-Gyoo, Cha, Dae-Ryong, Kang, Young-Sun, Han, Kum-Hyun, Kim, Hyoung-Kyu, Han, Jee-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2005
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891411/
https://www.ncbi.nlm.nih.gov/pubmed/15906952
http://dx.doi.org/10.3904/kjim.2005.20.1.40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891411/
https://www.ncbi.nlm.nih.gov/pubmed/15906952
http://dx.doi.org/10.3904/kjim.2005.20.1.40

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